CTH anticorps (AA 1-70)
Aperçu rapide pour CTH anticorps (AA 1-70) (ABIN7148969)
Antigène
Voir toutes CTH AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-70
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Fonction
- CTH Antibody
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Réactivité croisée
- Souris, Rat
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Human Cystathionine gamma-lyase protein (1-70AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))
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Autre désignation
- CTH
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Sujet
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Background: Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function.
Aliases: CGL_HUMAN antibody, CTH antibody, cystathionase (cystathionine gamma-lyase) antibody, Cystathionine gamma lyase antibody, Cystathionine gamma-lyase antibody, Cysteine desulfhydrase antibody, Gamma cystathionase antibody, Gamma-cystathionase antibody, Homoserine deaminase antibody, Homoserine dehydratase antibody, MGC9471 antibody
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UniProt
- P32929
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Pathways
- ER-Nucleus Signaling, L'effet Warburg
Antigène
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