NCK1 anticorps (AA 58-377)

N° du produit ABIN7149352

Cet anticorps anti-NCK1 est un anticorps Lapin Polyclonal détectant NCK1 dans WB, IHC et ELISA. Adapté pour Humain.

Aperçu rapide pour NCK1 anticorps (AA 58-377) (ABIN7149352)

Antigène: NCK1 (NCK Adaptor Protein 1 (NCK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-NCK1 anticorps

Épitope: AA 58-377

Fonction: NCK1 Antibody

Réactivité croisée: Rat

Purification: Antigen Affinity purified

Immunogène: Recombinant Human Cytoplasmic protein NCK1 protein (58-377AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NCK1

Antigène: NCK1 (NCK Adaptor Protein 1 (NCK1))

Autre désignation: NCK1

Sujet:

Background: Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. Modulates the activation of EIF2AK2/PKR by dsRNA. May play a role in cell adhesion and migration through interaction with ephrin receptors.

Aliases: Cytoplasmic protein NCK1 antibody, Melanoma Nck protein antibody, MGC12668 antibody, NCK 1 antibody, NCK adaptor protein 1 antibody, NCK alpha antibody, NCK antibody, NCK tyrosine kinase antibody, Nck-1 antibody, NCK1 antibody, NCK1_HUMAN antibody, NCKalpha antibody, Non catalytic region of tyrosine kinase antibody, SH2/SH3 adaptor protein NCK alpha antibody, SH2/SH3 adaptor protein NCK-alpha antibody

UniProt: P16333

Pathways: TCR Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals