NDEL1 anticorps (NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1) (pSer242) (Cy5.5)

Details for Product anti-NDEL1 Antibody No. ABIN710821
Antigène
  • EOPA
  • MITAP1
  • NDE1L1
  • NDE2
  • NUDEL
  • NUDE2
  • Nudel
  • 2600006O07Rik
  • mNudel
  • wu:fi23c04
  • wu:fi23e06
  • eopa
  • mitap1
  • ndel1
  • ndel1-a
  • ndel1-b
  • nudel
  • nudE neurodevelopment protein 1 like 1
  • nudE neurodevelopment protein 1-like 1
  • nudE neurodevelopment protein 1-like 1b
  • nudE neurodevelopment protein 1 like 1 L homeolog
  • NDEL1
  • Ndel1
  • ndel1b
  • ndel1.L
Épitope
pSer242
24
15
14
7
4
2
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
140
105
101
4
2
Hôte
Lapin
118
21
1
Clonalité
Polyclonal
Conjugué
Cet anticorp NDEL1 est conjugé à/à la Cy5.5
7
7
7
7
7
7
7
4
4
4
4
4
4
3
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
73
51
21
21
20
18
18
3
2
1
1
1
1
Options
Immunogène KLH conjugated synthetic phosphopeptide derived from human NDEL1 around the phosphorylation site of Ser242
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others NDEL1 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation Ndel1 (NDEL1 Antibody Extrait)
Sujet

Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome. Also required during brain development for the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Plays a role, together with DISC1, in the regulation of neurite outgrowth. Required for mitosis in some cell types but appears to be dispensible for mitosis in cortical neuronal progenitors, which instead requires NDE1. Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL.

Subcellular location: Cytoplasm

Synonyms: EOPA, NDE2, NUDEL, MITAP1, NDE1L1, Nuclear distribution protein nudE-like 1, Protein Nudel, Mitosin-associated protein 1, NDEL1

ID gène 81565
UniProt Q9GZM8
Pathways Regulation of Cell Size
Indications d'application IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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