DNAJA3 anticorps (AA 86-184) (HRP)

N° du produit ABIN7150501

Détail du produit anti-DNAJA3 anticorps (HRP)

Antigène: DNAJA3 (DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3))

Épitope: AA 86-184

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNAJA3 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human DnaJ homolog subfamily A member 3, mitochondrial protein (86-184AA )

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DNAJA3

Antigène: DNAJA3 (DnaJ (Hsp40) Homolog, Subfamily A, Member 3 (DNAJA3))

Autre désignation: DNAJA3 (DNAJA3 Produits)

Synonymes: anticorps Tid-1, anticorps 1200003J13Rik, anticorps 1810053A11Rik, anticorps C81173, anticorps Tid1l, anticorps HCA57, anticorps TID1, anticorps hTID-1, anticorps DnaJ heat shock protein family (Hsp40) member A3, anticorps Dnaja3, anticorps DNAJA3

Sujet:

Background: Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C, in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma-mediated transcriptional activity. Isoform 2 may play a role in neuromuscular junction development as an effector of the MUSK signaling pathway.

Aliases: DNAJA3 antibody, HCA57 antibody, TID1DnaJ homolog subfamily A member 3 antibody, mitochondrial antibody, DnaJ protein Tid-1 antibody, hTid-1 antibody, Hepatocellular carcinoma-associated antigen 57 antibody, Tumorous imaginal discs protein Tid56 homolog antibody

UniProt: Q96EY1

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity