DNAJC1 anticorps (AA 521-793)

N° du produit ABIN7150537

Détail du produit anti-DNAJC1 anticorps

Antigène: DNAJC1 (DnaJ (Hsp40) Homolog, Subfamily C, Member 1 (DNAJC1))

Épitope: AA 521-793

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNAJC1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Rat

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human DnaJ homolog subfamily C member 10 protein (521-793AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DNAJC1

Antigène: DNAJC1 (DnaJ (Hsp40) Homolog, Subfamily C, Member 1 (DNAJC1))

Autre désignation: DNAJC1 (DNAJC1 Produits)

Synonymes: anticorps dnajc1l, anticorps zgc:152779, anticorps DNAJL1, anticorps ERdj1, anticorps HTJ1, anticorps MTJ1, anticorps 4733401K02Rik, anticorps AA960110, anticorps D230036H06Rik, anticorps Dnajl1, anticorps ERj1p, anticorps DnaJ heat shock protein family (Hsp40) member C1, anticorps DnaJ (Hsp40) homolog, subfamily C, member 1, anticorps DnaJ heat shock protein family (Hsp40) member C1 S homeolog, anticorps dnajc1, anticorps DNAJC1, anticorps Dnajc1, anticorps dnajc1.S

Sujet:

Background: Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.

Aliases: DNAJC10 antibody, ERDJ5 antibody, UNQ495/PRO1012DnaJ homolog subfamily C member 10 antibody, EC 1.8.4.- antibody, Endoplasmic reticulum DNA J domain-containing protein 5 antibody, ER-resident protein ERdj5 antibody, ERdj5 antibody, Macrothioredoxin antibody, MTHr antibody

UniProt: Q8IXB1

Pathways: Chromatin Binding