EPHA1 anticorps (AA 296-414)

N° du produit ABIN7151827

Détail du produit anti-EPHA1 anticorps

Antigène: EPHA1 (Ephrin Type A Receptor 1 (EPHA1))

Épitope: AA 296-414

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPHA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Ephrin type-A receptor 1 protein (296-414AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur EPHA1

Antigène: EPHA1 (Ephrin Type A Receptor 1 (EPHA1))

Autre désignation: EPHA1 (EPHA1 Produits)

Synonymes: anticorps EPH, anticorps EPHT, anticorps EPHT1, anticorps 5730453L17Rik, anticorps AL033318, anticorps Eph, anticorps Esk, anticorps EPHA9, anticorps EPH receptor A1, anticorps Eph receptor A1, anticorps EPHA1, anticorps Epha1

Sujet:

Background: Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis.

Aliases: EPH antibody, EPH receptor A1 antibody, EPH tyrosine kinase 1 antibody, EPH tyrosine kinase antibody, Epha1 antibody, EPHA1_HUMAN antibody, Ephrin receptor Eph A1 antibody, Ephrin type A receptor 1 antibody, Ephrin type-A receptor 1 antibody, EPHT 1 antibody, EPHT antibody, EPHT1 antibody, Erythropoietin producing hepatoma amplified sequence antibody, Erythropoietin-producing hepatoma receptor antibody, Esk antibody, hEpha1 antibody, MGC163163 antibody, Oncogene EPH antibody, Soluble EPHA1 variant 1 antibody, Soluble EPHA1 variant 2 antibody, Tyrosine protein kinase receptor EPH antibody, Tyrosine-protein kinase receptor EPH antibody

UniProt: P21709