ELF3 anticorps (AA 147-371)

N° du produit ABIN7152094

Détail du produit anti-ELF3 anticorps

Antigène: ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))

Épitope: AA 147-371

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ELF3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human ETS-related transcription factor Elf-3 protein (147-371AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:500-1:1000, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ELF3

Antigène: ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))

Autre désignation: ELF3 (ELF3 Produits)

Synonymes: anticorps ert, anticorps esx, anticorps epr-1, anticorps ese-1, anticorps ESE-1, anticorps ESX, anticorps jen, anticorps EPR-1, anticorps ERT, anticorps E74 like ETS transcription factor 3, anticorps E74-like factor 3, anticorps elf3, anticorps Elf3, anticorps ELF3

Sujet:

Background: Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).

Aliases: E74 like factor 3 antibody, E74 like factor 3 ets domain transcription factor antibody, E74 like factor 3 ets domain transcription factor epithelial specific antibody, E74 like factor 3 ETS domain transcription factor serine box epithelial specific antibody, E74-like factor 3 antibody, Elf3 antibody, ELF3_HUMAN antibody, Epithelial restricted with serine box antibody, Epithelial-restricted with serine box antibody, Epithelium restricted Ets protein ESX antibody, Epithelium specific Ets factor 1 antibody, Epithelium specific Ets transcription factor 1 antibody, Epithelium-restricted Ets protein ESX antibody, Epithelium-specific Ets transcription factor 1 antibody, EPR 1 antibody, EPR1 antibody, ERT antibody, ESE-1 antibody, ESX antibody, Ets domain transcription factor serine box antibody, Ets domain transcription factor serine box epithelial specific antibody, Ets transcription factor antibody, ETS-related transcription factor Elf-3 antibody, jen antibody, MGC139318 antibody

UniProt: P78545