GZMB anticorps (AA 21-247)

N° du produit ABIN7154415

L’anticorps Lapin Polyclonal anti-GZMB a été validé pour IHC, ELISA et IF. Il convient pour détecter GZMB dans des échantillons de Humain.

Aperçu rapide pour GZMB anticorps (AA 21-247) (ABIN7154415)

Antigène: GZMB (Granzyme B (GZMB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GZMB est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-GZMB anticorps

Épitope: AA 21-247

Fonction: GZMB Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Granzyme B protein (21-247AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GZMB

Antigène: GZMB (Granzyme B (GZMB))

Autre désignation: GZMB

Sujet:

Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Aliases: C11 antibody, Cathepsin G like 1 antibody, Cathepsin G-like 1 antibody, CCPI antibody, CGL 1 antibody, CGL1 antibody, CSP B antibody, CSPB antibody, CTLA 1 antibody, CTLA-1 antibody, CTLA1 antibody, CTSGL1 antibody, Cytotoxic serine protease B antibody, Cytotoxic T lymphocyte associated serine esterase 1 antibody, Cytotoxic T lymphocyte proteinase 2 antibody, Cytotoxic T-lymphocyte proteinase 2 antibody, Fragmentin 2 antibody, Fragmentin-2 antibody, GRAB_HUMAN antibody, Granzyme 2 antibody, Granzyme B (granzyme 2, cytotoxic T lymphocyte associated serine esterase 1) antibody, Granzyme B antibody, Granzyme-2 antibody, GranzymeB antibody, GRB antibody, Gzmb antibody, Hlp antibody, Human lymphocyte protein antibody, Lymphocyte protease antibody, Protease, serine, B antibody, SECT antibody, T cell serine protease 1 3E antibody, T cell serine protease 1-3E antibody, T-cell serine protease 1-3E antibody

UniProt: P10144

Pathways: Apoptose, Caspase Cascade in Apoptosis