PTPN7 anticorps (pSer246) (Biotin)

N° du produit ABIN711328

Détail du produit anti-PTPN7 anticorps (Biotin)

Antigène: PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))

Épitope: pSer246

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPN7 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris

Homologie: Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from mouse PTPN7 around the phosphorylation site of Ser246

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur PTPN7

Antigène: PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))

Autre désignation: PTPN7 (PTPN7 Produits)

Synonymes: anticorps BPTP-4, anticorps HEPTP, anticorps LC-PTP, anticorps LPTP, anticorps PTPNI, anticorps C920001D21Rik, anticorps Heptp, anticorps Lcptp, anticorps protein tyrosine phosphatase, non-receptor type 7, anticorps PTPN7, anticorps Ptpn7

Sujet:

Synonyms: PTPN7phospho S246, BPTP 4, BPTP4, Dual specicity phosphatase 1, Hematopoietic protein tyrosine phosphatase, LC PTP, LCPTP, LPTP, Protein tyrosine phoshatase non receptor type stress induced, Protein tyrosine phoshatase nonreceptor type stress induced, Protein tyrosine phosphatase LC PTP, Protein tyrosine phosphatase non receptor type 7, PTPN 7, PTPNI, Tyrosine protein phosphatase non receptor type 7, PTN7_HUMAN.

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].

ID gène: 5778