SUV39H2 anticorps (AA 201-410)

N° du produit ABIN7155529

Cet anticorps anti-SUV39H2 est un anticorps Lapin Polyclonal détectant SUV39H2 dans WB, ELISA et IHC. Adapté pour Humain.

Aperçu rapide pour SUV39H2 anticorps (AA 201-410) (ABIN7155529)

Antigène: SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUV39H2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SUV39H2 anticorps

Épitope: AA 201-410

Fonction: SUV39H2 Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Histone-lysine N-methyltransferase SUV39H2 protein (201-410AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SUV39H2

Antigène: SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))

Autre désignation: SUV39H2

Sujet:

Background: Histone methyltransferase that specifically trimethylates \\\'Lys-9\\\' of histone H3 using monomethylated H3 \\\'Lys-9\\\' as substrate. H3 \\\'Lys-9\\\' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 \\\'Lys-9\\\' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May participate in regulation of higher-order chromatin organization during spermatogenesis. Recruited by the large PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1, contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 \\\'Lys-9\\\' trimethylation.

Aliases: FLJ23414 antibody, H3 K9 HMTase 2 antibody, H3-K9-HMTase 2 antibody, Histone H3 K9 methyltransferase 2 antibody, Histone H3-K9 methyltransferase 2 antibody, Histone lysine N methyltransferase H3 lysine 9 specific 2 antibody, Histone lysine N methyltransferase SUV39H2 antibody, Histone-lysine N-methyltransferase SUV39H2 antibody, KMT1B antibody, Lysine N methyltransferase 1B antibody, Lysine N-methyltransferase 1B antibody, sSuppressor of variegation 3 9 homolog 2 (Drosophila) antibody, Su(var)3 9 Drosophila homolog of 2 antibody, Su(var)3 9 homolog 2 antibody, Su(var)3-9 homolog 2 antibody, Suppressor of variegation 3 9 homolog 2 antibody, Suppressor of variegation 3-9 homolog 2 antibody, Suv39h2 antibody, SUV92_HUMAN antibody

UniProt: Q9H5I1