PIK3R1 anticorps (pTyr467) (Cy5)
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- Antigène Voir toutes PIK3R1 (PI3K p85a) Anticorps
- PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))
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Épitope
- pTyr467
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Reactivité
- Humain, Souris, Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PIK3R1 est conjugé à/à la Cy5
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Réactivité croisée
- Humain, Souris, Porc
- Homologie
- Rat,Dog,Cow,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic phosphopeptide derived from human PIK3R1 around the phosphorylation site of Tyr467 [RL(p-Y)EE]
- Isotype
- IgG
- Top Product
- Discover our top product PI3K p85a Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))
- Autre désignation
- PIK3R1 (PI3K p85a Produits)
- Synonymes
- anticorps PI3CG, anticorps PI3K, anticorps PI3Kgamma, anticorps PIK3, anticorps AGM7, anticorps GRB1, anticorps p85, anticorps p85-ALPHA, anticorps PI3KA, anticorps AA414921, anticorps C530050K14, anticorps p50alpha, anticorps p55alpha, anticorps p85alpha, anticorps wu:fb65b05, anticorps phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma, anticorps phosphoinositide-3-kinase regulatory subunit 1, anticorps phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta, anticorps phosphoinositide-3-kinase, regulatory subunit 1 (alpha), anticorps PIK3CG, anticorps PIK3R1, anticorps Pik3r1, anticorps Pik3cb, anticorps pik3r1
- Sujet
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Synonyms: PIK3R1phospho Y467, GRB1, p50 alpha, p55 alpha, p85 alpha, p85, Phosphatidylinositol 3 kinase associated p85 alpha, Phosphatidylinositol 3 kinase regulatory 1, Phosphatidylinositol 3 kinase regulatory alpha subunit, Phosphoinositide 3 kinase regulatory subunit polypeptide 1 p85 alpha, PI3 kinase p85 alpha subunit, PI3 kinase p85 subunit alpha, PI3K , PIK3R1, PtdIns 3 kinase p85 alpha.
Background: The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 alpha). p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.
- ID gène
- 5295
- Pathways
- TCR Signaling, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling, L'effet Warburg
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