Meprin B anticorps (AA 480-652)

N° du produit ABIN7159412

Détail du produit anti-Meprin B anticorps

Antigène: Meprin B (MEP1B) (Meprin A, beta (MEP1B))

Épitope: AA 480-652

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Meprin B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain, Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Meprin A subunit beta protein (480-652AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Meprin B

Antigène: Meprin B (MEP1B) (Meprin A, beta (MEP1B))

Autre désignation: MEP1B (MEP1B Produits)

Synonymes: anticorps MEP1B, anticorps si:ch211-191a24.6, anticorps zgc:153272, anticorps Mep-1b, anticorps meprin A subunit beta, anticorps meprin A, beta, anticorps meprin 1 beta, anticorps MEP1B, anticorps LOC100031050, anticorps mep1b, anticorps LOC100545010, anticorps Mep1b

Sujet:

Background: Membrane metallopeptidase that sheds many membrane-bound proteins. Exhibits a strong preference for acidic amino acids at the P1\\\' position. Known substrates include: FGF19, VGFA, IL1B, IL18, procollagen I and III, E-cadherin, KLK7, gastrin, ADAM10, tenascin-C. The presence of several pro-inflammatory cytokine among substrates implicate MEP1B in inflammation. It is also involved in tissue remodeling due to its capability to degrade extracellular matrix components.

Aliases: Endopeptidase 2 antibody, Endopeptidase-2 antibody, kinase splitting membranal proteinase antibody, KSMP antibody, Mep1b antibody, MEP1B_HUMAN antibody, Meprin 1 beta subunit antibody, Meprin A beta antibody, Meprin A beta subunit precursor antibody, Meprin A subunit beta antibody, Meprin B antibody, N benzoyl L tyrosyl P amino benzoic acid hydrolase beta subunit antibody, N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta antibody, PABA peptide hydrolase antibody, PPH beta antibody

UniProt: Q16820