Meprin B anticorps

N° du produit ABIN7229644

Cet anticorps anti-Meprin B Polyclonal Lapin (ABIN7229644) détecte spécifiquement Meprin B dans WB et ELISA. L’anticorps est réactif avec des échantillons de Rat, Humain et Souris.

Aperçu rapide pour Meprin B anticorps (ABIN7229644)

Antigène: Meprin B (MEP1B) (Meprin A, beta (MEP1B))

Reactivité: Rat, Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Meprin B est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Meprin B anticorps

Fonction: Rabbit Anti-MEP1B Polyclonal Antibody

Specificité: The antibody detects endogenous levels of MEP1B protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human MEP1B protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Meprin B

Antigène: Meprin B (MEP1B) (Meprin A, beta (MEP1B))

Autre désignation: MEP1B

Sujet: Meprin A subunit beta, Endopeptidase-2, Meprin B, N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta, PABA peptide hydrolase, PPH betaMeprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.

Poids moléculaire: 77kD

ID gène: 4225

UniProt: Q16820