Meprin B anticorps (AA 73-489)

N° du produit ABIN8009154

L’anticorps anti-Meprin B Polyclonal Lapin est utilisé pour la détection de Meprin B dans des échantillons de Rat, Humain et Souris. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour Meprin B anticorps (AA 73-489) (ABIN8009154)

Antigène: Meprin B (MEP1B) (Meprin A, beta (MEP1B))

Reactivité: Rat, Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Meprin B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Classe de qualité: Carrier-free

Détail du produit anti-Meprin B anticorps

Épitope: AA 73-489

Fonction: Anti-MEP1B Antibody

Homologie: Human MEP1B shares 82.3%,81.5% amino acid (aa) sequence identity with mouse,rat MEP1B,respectively.

Attributs du produit: Anti-MEP1B Antibody. Tested in WB, IF, IHC, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MEP1B recombinant protein (Position: H73-Q489). Human MEP1B shares 82.3% and 81.5% amino acid (aa) sequence identity with mouse and rat MEP1B, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat Immunofluorescence, 5 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Meprin B

Antigène: Meprin B (MEP1B) (Meprin A, beta (MEP1B))

Autre désignation: MEP1B

Sujet:

Background: Meprin A subunit beta is a protein that in humans is encoded by the MEP1B gene. Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.

Gene Full Name: meprin A subunit beta

Poids moléculaire: 97 kDa

ID gène: 4225

UniProt: Q16820