MYD88 anticorps (AA 1-282) (Biotin)

N° du produit ABIN7160473

Cet anticorps anti-MYD88 est un anticorps Lapin Polyclonal détectant MYD88 dans ELISA. Adapté pour Humain.

Aperçu rapide pour MYD88 anticorps (AA 1-282) (Biotin) (ABIN7160473)

Antigène: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYD88 est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-MYD88 anticorps (Biotin)

Épitope: AA 1-282

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Myeloid differentiation primary response protein MyD88 protein (1-282AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MYD88

Antigène: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Autre désignation: MYD88

Sujet:

Background: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine.

Aliases: Mutant myeloid differentiation primary response 88 antibody, MYD 88 antibody, Myd88 antibody, MYD88_HUMAN antibody, MYD88D antibody, Myeloid differentiation marker 88 antibody, Myeloid differentiation primary response 88 antibody, Myeloid differentiation primary response gene (88) antibody, Myeloid differentiation primary response gene 88 antibody, Myeloid differentiation primary response gene antibody, Myeloid differentiation primary response protein MyD88 antibody, OTTHUMP00000161718 antibody, OTTHUMP00000208595 antibody, OTTHUMP00000209058 antibody, OTTHUMP00000209059 antibody, OTTHUMP00000209060 antibody

UniProt: Q99836

Pathways: Signalisation NF-kappaB, Signalisation TLR, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades