NLRP1 anticorps (AA 589-655) (HRP)
Aperçu rapide pour NLRP1 anticorps (AA 589-655) (HRP) (ABIN7160824)
Antigène
Voir toutes NLRP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 589-655
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human NACHT, LRR and PYD domains-containing protein 10 protein (589-655AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
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Autre désignation
- NLRP1
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Sujet
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Background: Inhibits autoprocessing of CASP1, CASP1-dependent IL1B secretion, PYCARD aggregation and PYCARD-mediated apoptosis but not apoptosis induced by FAS or BID. Displays anti-inflammatory activity. Plays a role in adaptive immunity through control of dendritic cell-mediated transport of antigen to the lymph nodes from peripheral sites. Required for immunity against C.albicans infection. Involved in the innate immune response by contributing to proinflammatory cytokine release in response to invasive bacterial infection.
Aliases: CLR11.1 antibody, NACHT, leucine rich repeat and PYD containing 10 antibody, NACHT, LRR and PYD domains containing protein 10 antibody, NACHT, LRR and PYD domains-containing protein 10 antibody, NAL10_HUMAN antibody, NALP10 antibody, NLR family, pyrin domain containing 10 antibody, Nlrp10 antibody, NOD8 antibody, Nucleotide-binding oligomerization domain protein 8 antibody, Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10 antibody, PAN5 antibody, PYNOD antibody
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UniProt
- Q86W26
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Pathways
- Positive Regulation of Endopeptidase Activity, Inflammasome
Antigène
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