ATP8A1 anticorps (AA 448-545) (Biotin)

N° du produit ABIN7163367

Détail du produit anti-ATP8A1 anticorps (Biotin)

Antigène: ATP8A1 (ATPase, Class I, Type 8A, Member 1 (ATP8A1))

Épitope: AA 448-545

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP8A1 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Phospholipid-transporting ATPase IA protein (448-545AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ATP8A1

Antigène: ATP8A1 (ATPase, Class I, Type 8A, Member 1 (ATP8A1))

Autre désignation: ATP8A1 (ATP8A1 Produits)

Synonymes: anticorps ATPASEII, anticorps ATPIA, anticorps ATPP2, anticorps AI481521, anticorps AI853962, anticorps APLT, anticorps AW743152, anticorps AW822227, anticorps Atp3a2, anticorps B230107D19Rik, anticorps ClassI, anticorps mKIAA4233, anticorps ATPase phospholipid transporting 8A1, anticorps ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1, anticorps Atp8a1, anticorps ATP8A1

Sujet:

Background: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Acts as aminophospholipid translocase at the plasma membrane in neuronal cells.

Aliases: ATP8A1 antibody, ATPIAPhospholipid-transporting ATPase IA antibody, EC 7.6.2.1 antibody, ATPase class I type 8A member 1 antibody, Chromaffin granule ATPase II antibody, P4-ATPase flippase complex alpha subunit ATP8A1 antibody

UniProt: Q9Y2Q0