ATP8A2 anticorps (AA 358-570) (Biotin)

N° du produit ABIN7163371

Détail du produit anti-ATP8A2 anticorps (Biotin)

Antigène: ATP8A2 (ATPase, Class I, Type 8A, Member 2 (ATP8A2))

Épitope: AA 358-570

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP8A2 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Phospholipid-transporting ATPase IB protein (358-570AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ATP8A2

Antigène: ATP8A2 (ATPase, Class I, Type 8A, Member 2 (ATP8A2))

Autre désignation: ATP8A2 (ATP8A2 Produits)

Synonymes: anticorps AI415030, anticorps Atpc1b, anticorps Ib, anticorps ATP, anticorps ATPIB, anticorps CAMRQ4, anticorps IB, anticorps ML-1, anticorps ATPase, aminophospholipid transporter-like, class I, type 8A, member 2, anticorps ATPase phospholipid transporting 8A2, anticorps Atp8a2, anticorps ATP8A2

Sujet:

Background: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. Reconstituted to liposomes, the ATP8A2:TMEM30A flippase complex predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE). Proposed to function in the generation and maintenance of phospholipid asymmetry in photoreceptor disk membranes and neuronal axon membranes. May be involved in vesicle trafficking in neuronal cells. Involved in regulation of neurite outgrowth, acting in synergy with TMEM30A. Required for normal visual and auditory function, involved in photoreceptor and inner ear spiral ganglion cell survival.

Aliases: AT8A2_HUMAN antibody, ATP antibody, Atp8a2 antibody, ATPase aminophospholipid transporter class I type 8A member 2 antibody, ATPase aminophospholipid transporter like class I type 8A member 2 antibody, ATPase class I type 8A member 2 antibody, ATPase phospholipid transporting 8A2 antibody, ATPIB antibody, CAMRQ4 antibody, EC=3.6.3.1 antibody, IB antibody, ML-1 antibody, ML1 antibody, P4 ATPase flippase complex alpha subunit ATP8A2 antibody, Probable phospholipid-transporting ATPase IB antibody

UniProt: Q9NTI2