ATP8B1 anticorps (AA 217-330)

N° du produit ABIN7163374

Détail du produit anti-ATP8B1 anticorps

Antigène: ATP8B1 (ATPase, Class I, Type 8B, Member 1 (ATP8B1))

Épitope: AA 217-330

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP8B1 est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Phospholipid-transporting ATPase IC protein (217-330AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ATP8B1

Antigène: ATP8B1 (ATPase, Class I, Type 8B, Member 1 (ATP8B1))

Autre désignation: ATP8B1 (ATP8B1 Produits)

Synonymes: anticorps bric, anticorps fic1, anticorps pfic, anticorps atpic, anticorps pfic1, anticorps MGC69272, anticorps ATPIC, anticorps BRIC, anticorps FIC1, anticorps ICP1, anticorps PFIC, anticorps PFIC1, anticorps AI451886, anticorps Ic, anticorps ATPase phospholipid transporting 8B1, anticorps ATPase phospholipid transporting 8B1 S homeolog, anticorps ATPase, class I, type 8B, member 1, anticorps Atp8b1, anticorps ATP8B1, anticorps atp8b1, anticorps atp8b1.S

Sujet:

Background: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. May play a role in asymmetric distribution of phospholipids in the canicular membrane. May have a role in transport of bile acids into the canaliculus, uptake of bile acids from intestinal contents into intestinal mucosa or both. In cooperation with ABCB4 may be involved in establishing integrity of the canalicular membrane thus protecting hepatocytes from bile salts. Together with TMEM30A is involved in uptake of the synthetic drug alkylphospholipid perifosine. Involved in the microvillus formation in polarized epithelial cells, the function seems to be independent from its flippase activity. Required for the preservation of cochlear hair cells in the inner ear. May act as cardiolipin transporter during inflammatory injury.

Aliases: AT8B1_HUMAN antibody, ATP8B1 antibody, ATPase class I type 8B member 1 antibody, ATPase, aminophospholipid transporter, class I, type 8B, member 1 antibody, ATPIC antibody, BRIC antibody, E1-E2 ATPase antibody, Familial intrahepatic cholestasis type 1 antibody, FIC1 antibody, OTTHUMP00000163615 antibody, PFIC antibody, PFIC1 antibody, Phospholipid transporting ATPase IC antibody, Probable phospholipid-transporting ATPase IC antibody

UniProt: O43520