KCNC3 anticorps (AA 638-745) (HRP)

N° du produit ABIN7163972

Détail du produit anti-KCNC3 anticorps (HRP)

Antigène: KCNC3 (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 3 (KCNC3))

Épitope: AA 638-745

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNC3 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Potassium voltage-gated channel subfamily C member 3 protein (638-745AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KCNC3

Antigène: KCNC3 (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 3 (KCNC3))

Autre désignation: KCNC3 (KCNC3 Produits)

Synonymes: anticorps kcnc3-A, anticorps Kv3.1, anticorps KShIIID, anticorps Kcr2-3, anticorps Kv3.3, anticorps KSHIIID, anticorps KV3.3, anticorps SCA13, anticorps kcnc1, anticorps kshiiid, anticorps kv3.3, anticorps sca13, anticorps potassium voltage-gated channel subfamily C member 3, anticorps potassium channel, voltage gated Shaw related subfamily C, member 1 S homeolog, anticorps potassium voltage gated channel, Shaw-related subfamily, member 3, anticorps potassium channel, voltage gated Shaw related subfamily C, member 3 L homeolog, anticorps potassium voltage-gated channel, Shaw-related subfamily, member 3, anticorps KCNC3, anticorps kcnc1.S, anticorps Kcnc3, anticorps kcnc3.L

Sujet:

Background: Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. The channel opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient. The channel displays rapid activation and inactivation kinetics (PubMed:10712820, PubMed:26997484, PubMed:22289912, PubMed:23734863, PubMed:16501573, PubMed:19953606, PubMed:21479265, PubMed:25756792). It plays a role in the regulation of the frequency, shape and duration of action potentials in Purkinje cells. Required for normal survival of cerebellar neurons, probably via its role in regulating the duration and frequency of action potentials that in turn regulate the activity of voltage-gated Ca(2+) channels and cellular Ca(2+) homeostasis (By similarity). Required for normal motor function (PubMed:23734863, PubMed:16501573, PubMed:19953606, PubMed:21479265, PubMed:25756792). Plays a role in the reorganization of the cortical actin cytoskeleton and the formation of actin veil structures in neuronal growth cones via its interaction with HAX1 and the Arp2/3 complex (PubMed:26997484).

Aliases: Kcnc3 antibody, KCNC3_HUMAN antibody, KSHIIID antibody, KV3.3 antibody, Potassium voltage gated channel Shaw related subfamily member 3 antibody, Potassium voltage gated channel subfamily C member 3 antibody, Potassium voltage-gated channel subfamily C member 3 antibody, SCA13 antibody, Shaw related subfamily, member 3 antibody, Shaw related voltage gated potassium channel protein 3 antibody, Spinocerebellar ataxia 13 antibody, Voltage gated potassium channel protein KV3.3 antibody, Voltage gated potassium channel subunit Kv3.3 antibody, Voltage-gated potassium channel subunit Kv3.3 antibody

UniProt: Q14003