RSPO1 anticorps (AA 21-263)

N° du produit ABIN7166935

Cet anticorps anti-RSPO1 est un anticorps Polyclonal produit chez le Lapin, détectant RSPO1 dans IHC et ELISA. Convient pour Humain.

Aperçu rapide pour RSPO1 anticorps (AA 21-263) (ABIN7166935)

Antigène: RSPO1 (R-Spondin 1 (RSPO1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RSPO1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-RSPO1 anticorps

Épitope: AA 21-263

Fonction: RSPO1 Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human R-spondin-1 protein (21-263AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RSPO1

Antigène: RSPO1 (R-Spondin 1 (RSPO1))

Autre désignation: RSPO1

Sujet:

Background: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determination.

Aliases: CRISTIN3, FLJ40906, hRspo1, R spondin homolog, R spondin homolog (Xenopus laevis), R spondin1, R-spondin-1, Roof plate specific spondin, Roof plate-specific spondin-1, RP11-566C13.1, RSPO, Rspo1, RSPO1_HUMAN

UniProt: Q2MKA7