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RSPO1 anticorps (AA 21-263)

Cet anticorps anti-RSPO1 est un anticorps Lapin Polyclonal détectant RSPO1 dans IHC et ELISA. Adapté pour Humain.
N° du produit ABIN7166935

Aperçu rapide pour RSPO1 anticorps (AA 21-263) (ABIN7166935)

Antigène

Voir toutes RSPO1 Anticorps
RSPO1 (R-Spondin 1 (RSPO1))

Reactivité

  • 45
  • 38
  • 33
  • 15
  • 15
  • 15
  • 15
  • 15
Humain

Hôte

  • 46
  • 8
  • 1
Lapin

Clonalité

  • 47
  • 8
Polyclonal

Conjugué

  • 24
  • 6
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Cet anticorp RSPO1 est non-conjugé

Application

  • 38
  • 15
  • 13
  • 11
  • 10
  • 7
  • 6
  • 6
  • 2
  • 2
  • 2
  • 1
  • 1
Immunohistochemistry (IHC), ELISA
  • Épitope

    • 15
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 21-263

     Réactivité croisée

    Humain

    Purification

    Antigen Affinity Purified

    Immunogène

    Recombinant Human R-spondin-1 protein (21-263AA)

    Isotype

    IgG
  • Indications d'application

    Recommended dilution: IHC:1:20-1:200,

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène

    RSPO1 (R-Spondin 1 (RSPO1))

    Autre désignation

    RSPO1

    Sujet

    Background: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determination.

    Aliases: CRISTIN3, FLJ40906, hRspo1, R spondin homolog, R spondin homolog (Xenopus laevis), R spondin1, R-spondin-1, Roof plate specific spondin, Roof plate-specific spondin-1, RP11-566C13.1, RSPO, Rspo1, RSPO1_HUMAN

    UniProt

    Q2MKA7
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