ERN1 anticorps (AA 493-561)

N° du produit ABIN7169238

Détail du produit anti-ERN1 anticorps

Antigène: ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))

Épitope: AA 493-561

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERN1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Serine/threonine-protein kinase/endoribonuclease IRE1 protein (493-561AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ERN1

Antigène: ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))

Autre désignation: ERN1 (ERN1 Produits)

Synonymes: anticorps IRE1, anticorps IRE1P, anticorps IRE1a, anticorps hIRE1p, anticorps 9030414B18Rik, anticorps AI225830, anticorps C85377, anticorps Ire1a, anticorps Ire1alpha, anticorps Ire1p, anticorps RGD1559716, anticorps Ern1, anticorps Ire1, anticorps Ire1b, anticorps sb:eu1005, anticorps zgc:109932, anticorps endoplasmic reticulum to nucleus signaling 1, anticorps endoplasmic reticulum to nucleus signaling 2, anticorps endoplasmic reticulum (ER) to nucleus signalling 1, anticorps serine/threonine-protein kinase/endoribonuclease IRE1, anticorps endoplasmic reticulum (ER) to nucleus signalling 2, anticorps ERN1, anticorps ERN2, anticorps Ern1, anticorps LOC524719, anticorps Ern2, anticorps ern1

Sujet:

Background: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.

Aliases: Endoplasmic reticulum (ER) to nucleus signalling 1 antibody, Endoplasmic reticulum to nucleus signaling 1 antibody, Endoplasmic reticulum-to-nucleus signaling 1 antibody, Endoribonuclease antibody, ER to nucleus signaling 1 antibody, ERN 1 antibody, Ern1 antibody, ERN1_HUMAN antibody, hIRE 1p antibody, hIRE1p antibody, Inositol requiring 1 antibody, Inositol requiring 1, S. cerevisiae, homolog of antibody, Inositol requiring enzyme 1, S. cerevisiae, homolog of antibody, Inositol requiring protein 1 antibody, inositol-requiring enzyme 1 antibody, Inositol-requiring protein 1 antibody, IRE 1 antibody, IRE 1a antibody, IRE 1P antibody, Ire1 alpha antibody, Ire1-alpha antibody, IRE1a antibody, Ire1alpha antibody, IRE1P antibody, MGC163277 antibody, MGC163279 antibody, Protein kinase/endoribonuclease antibody, RGD1559716 antibody, Serine/threonine protein kinase/endoribonuclease IRE1 antibody

UniProt: O75460

Pathways: ER-Nucleus Signaling, Unfolded Protein Response