ERN1 anticorps (AA 282-433)

N° du produit ABIN969116

Il existe 3+ publications pour ce produit. L’anticorps anti-ERN1 Monoclonal Souris est utilisé pour la détection de ERN1 dans des échantillons de Humain. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour ERN1 anticorps (AA 282-433) (ABIN969116)

Antigène: ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ERN1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 9F2

Détail du produit anti-ERN1 anticorps

Épitope: AA 282-433

Fonction: ERN1 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human ERN1(aa282-433) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-ERN1 (ABIN969116)

Lin, Li, Yasumura, Cohen, Zhang, Panning, Shokat, Lavail, Walter: "IRE1 signaling affects cell fate during the unfolded protein response." dans: Science (New York, N.Y.), Vol. 318, Issue 5852, pp. 944-9, (2007) (PubMed).

Huang, Tan, Yoshida, Mori, Ma, Yen: "Activation of hepatitis B virus S promoter by a cell type-restricted IRE1-dependent pathway induced by endoplasmic reticulum stress." dans: Molecular and cellular biology, Vol. 25, Issue 17, pp. 7522-33, (2005) (PubMed).

Shang, Lehrman: "Discordance of UPR signaling by ATF6 and Ire1p-XBP1 with levels of target transcripts." dans: Biochemical and biophysical research communications, Vol. 317, Issue 2, pp. 390-6, (2004) (PubMed).

Détails sur ERN1

Antigène: ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))

Autre désignation: ERN1

Sujet: The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.

Poids moléculaire: 109 kDa

UniProt: O75460

Pathways: ER-Nucleus Signaling, Unfolded Protein Response