SIGIRR anticorps (AA 1-120)

N° du produit ABIN7169723

Détail du produit anti-SIGIRR anticorps

Antigène: SIGIRR (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR))

Épitope: AA 1-120

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIGIRR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain, Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Single Ig IL-1-related receptor protein (1-120AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SIGIRR

Antigène: SIGIRR (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR))

Autre désignation: SIGIRR (SIGIRR Produits)

Synonymes: anticorps TIR8, anticorps AI256711, anticorps sc:d148, anticorps RGD1306732, anticorps single Ig and TIR domain containing, anticorps single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, anticorps SIGIRR, anticorps Sigirr, anticorps sigirr

Sujet:

Background: Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.

Aliases: Ig IL1 related receptor antibody, MGC110992 antibody, SIGIR_HUMAN antibody, SIGIRR antibody, Single Ig IL 1 related receptor antibody, Single Ig IL-1-related receptor antibody, Single Ig IL-1R-related molecule antibody, Single Ig IL1R Related Molecule antibody, Single immunoglobulin and toll interleukin 1 receptor (TIR) domain antibody, Single immunoglobulin and toll interleukin 1 receptor domain antibody, Single immunoglobulin domain containing IL1R related protein antibody, Single immunoglobulin domain IL1R1 related antibody, Single immunoglobulin domain-containing IL1R-related protein antibody, TIR 8 antibody, TIR8 antibody, Toll/interleukin 1 receptor 8 antibody, Toll/interleukin-1 receptor 8 antibody

UniProt: Q6IA17

Pathways: Toll-Like Receptors Cascades