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SPOP-B anticorps (AA 48-374) (HRP)

SPOP-B Reactivité: Humain ELISA Hôte: Lapin Polyclonal HRP
N° du produit ABIN7170435
  • Antigène Voir toutes SPOP-B Anticorps
    SPOP-B (Speckle-Type POZ Protein (SPOP-B))
    Épitope
    • 15
    • 8
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 48-374
    Reactivité
    • 57
    • 18
    • 13
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 56
    • 4
    Lapin
    Clonalité
    • 56
    • 4
    Polyclonal
    Conjugué
    • 26
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SPOP-B est conjugé à/à la HRP
    Application
    • 49
    • 23
    • 13
    • 13
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Speckle-type POZ protein (48-374AA)
    Isotype
    IgG
    Top Product
    Discover our top product SPOP-B Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    SPOP-B (Speckle-Type POZ Protein (SPOP-B))
    Autre désignation
    SPOP (SPOP-B Produits)
    Synonymes
    anticorps BTBD32, anticorps TEF2, anticorps AI315626, anticorps Pcif1, anticorps zgc:64140, anticorps spop, anticorps tef2, anticorps speckle type BTB/POZ protein, anticorps speckle-type POZ protein, anticorps speckle type POZ protein S homeolog, anticorps SPOP, anticorps Spop, anticorps spop, anticorps spop.S
    Sujet

    Background: Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of H2AFY and BMI1, this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. The cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOP has higher ubiquitin ligase activity than the complex that contains the heterodimer formed by SPOP and SPOPL.

    Aliases: BTBD32 antibody, HIB homolog 1 antibody, Roadkill homolog 1 antibody, Speckle type POZ protein antibody, Speckle-type POZ protein antibody, SPOP antibody, SPOP_HUMAN antibody, TEF 2 antibody, TEF2 antibody

    UniProt
    O43791
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