SMARCD3 anticorps (AA 2-101) (HRP)

N° du produit ABIN7171082

Détail du produit anti-SMARCD3 anticorps (HRP)

Antigène: SMARCD3 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 3 (SMARCD3))

Épitope: AA 2-101

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMARCD3 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 protein (2-101AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SMARCD3

Antigène: SMARCD3 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 3 (SMARCD3))

Autre désignation: SMARCD3 (SMARCD3 Produits)

Synonymes: anticorps SMARCD3, anticorps baf60c, anticorps cracd3, anticorps rsc6p, anticorps BAF60C, anticorps CRACD3, anticorps Rsc6p, anticorps 1500001J14Rik, anticorps 2210409C08Rik, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 S homeolog, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b, anticorps SMARCD3, anticorps smarcd3.S, anticorps Smarcd3, anticorps smarcd3b

Sujet:

Background: Plays a role in ATP dependent nucleosome remodeling by SMARCA4 containing complexes. Stimulates nuclear receptor mediated transcription. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).

Aliases: 60 kDa BRG 1/Brm associated factor subunit C antibody, 60 kDa BRG-1/Brm-associated factor subunit C antibody, BAF60C antibody, BRG1 associated factor 60C antibody, BRG1-associated factor 60C antibody, Chromatin remodeling complex BAF60C subunit antibody, CRACD3 antibody, Mammalian chromatin remodeling complex BRG1 associated factor 60C antibody, MGC111010 antibody, Rsc6p antibody, Smarcd3 antibody, SMRD3_HUMAN antibody, SWI/SNF complex 60 kDa subunit C antibody, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily d member 3 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3, isoform 1 antibody, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 antibody, Swp73 like protein antibody

UniProt: Q6STE5

Pathways: Regulation of Lipid Metabolism by PPARalpha