RASGRF1 anticorps (pSer929)

N° du produit ABIN713201

Détail du produit anti-RASGRF1 anticorps

Antigène: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Épitope: pSer929

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASGRF1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human RasGRF1 around the phosphorylation site of Ser929

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur RASGRF1

Antigène: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Autre désignation: RASGRF1 (RASGRF1 Produits)

Synonymes: anticorps CDC25, anticorps CDC25L, anticorps GNRP, anticorps GRF1, anticorps GRF55, anticorps H-GRF55, anticorps PP13187, anticorps ras-GRF1, anticorps AI844718, anticorps CDC25Mm, anticorps Grf1, anticorps Grfbeta, anticorps P190-A, anticorps Ras-GRF1, anticorps p190, anticorps p190RhoGEF, anticorps cdc25, anticorps rasgrf1, anticorps Ras protein specific guanine nucleotide releasing factor 1, anticorps RAS protein-specific guanine nucleotide-releasing factor 1, anticorps Ras protein specific guanine nucleotide releasing factor 1 S homeolog, anticorps si:ch211-234p18.3, anticorps RASGRF1, anticorps Rasgrf1, anticorps rasgrf1.S, anticorps si:ch211-234p18.3, anticorps rasgrf1

Sujet:

Synonyms: RASGRF1phospho S929, RASGRF1phospho Ser929, p-RASGRF1S929, p-RASGRF1Ser929, CDC25, CDC25L, GNRP, GRF1, GRF55, Guanine nucleotide exchange factor, Guanine nucleotide releasing factor 55 kD, Guanine nucleotide releasing protein, HGRF55, PP13187, Ras protein specic guanine nucleotide releasing factor 1, Ras specic guanine nucleotide releasing factor, Ras specic guanine nucleotide releasing factor CDC25 homolog, Ras specic nucleotide exchange factor CDC25.

Background: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]

ID gène: 5923

Pathways: Signalisation RTK, Cycle Cellulaire, M Phase