RASGRF1 anticorps (pSer929) (Cy3)

N° du produit ABIN713204

L’anticorps Lapin Polyclonal anti-RASGRF1 a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter RASGRF1 dans des échantillons de Rat.

Aperçu rapide pour RASGRF1 anticorps (pSer929) (Cy3) (ABIN713204)

Antigène: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASGRF1 est conjugé à/à la Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-RASGRF1 anticorps (Cy3)

Épitope: pSer929

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human RasGRF1 around the phosphorylation site of Ser929

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur RASGRF1

Antigène: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Autre désignation: RASGRF1

Sujet:

Synonyms: RASGRF1phospho S929, RASGRF1phospho Ser929, p-RASGRF1S929, p-RASGRF1Ser929, CDC25, CDC25L, GNRP, GRF1, GRF55, Guanine nucleotide exchange factor, Guanine nucleotide releasing factor 55 kD, Guanine nucleotide releasing protein, HGRF55, PP13187, Ras protein specic guanine nucleotide releasing factor 1, Ras specic guanine nucleotide releasing factor, Ras specic guanine nucleotide releasing factor CDC25 homolog, Ras specic nucleotide exchange factor CDC25.

Background: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]

ID gène: 5923

Pathways: Signalisation RTK, Cycle Cellulaire, M Phase