NAMPT anticorps (AA 231-491) (HRP)
Aperçu rapide pour NAMPT anticorps (AA 231-491) (HRP) (ABIN7178976)
Antigène
Voir toutes NAMPT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 231-491
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Fonction
- Nampt Antibody, HRP conjugated
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Réactivité croisée
- Rat
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Purification
- Antigen Affinity purified & Affinity purified
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Pureté
- >95 %
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Immunogène
- Recombinant Rat Nampt protein (231-491AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))
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Autre désignation
- Nampt
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Sujet
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Background: Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression.
Aliases: Nampt antibody, Pbef1 antibody, Nicotinamide phosphoribosyltransferase antibody, NAmPRTase antibody, Nampt antibody, EC 2.4.2.12 antibody, Pre-B-cell colony-enhancing factor 1 homolog antibody, PBEF antibody, Visfatin antibody
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UniProt
- Q80Z29
Antigène
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