BAX anticorps (Thr167)

N° du produit ABIN7179980

Cet anticorps Lapin Polyclonal détecte spécifiquement BAX dans WB, ELISA et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour BAX anticorps (Thr167) (ABIN7179980)

Antigène: BAX (BCL2-Associated X Protein (BAX))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAX est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-BAX anticorps

Épitope: Thr167

Fonction: BAX (Ab-167) Antibody

Réactivité croisée: Souris

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized non-phosphopeptide derived from Human Bax around the phosphorylation site of threonine 167 (F-G-T(p)-P-T).

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur BAX

Antigène: BAX (BCL2-Associated X Protein (BAX))

Autre désignation: BAX

Sujet:

Background: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

Oltvai Z.N., Cell 74:609-619(1993).
Cuddeback S.M., J. Biol. Chem. 276:20559-20565(2001).
Guo B., Nature 423:456-461(2003)

Aliases: Apoptosis regulator BAX antibody, BAX antibody, Bax-protein antibody, BAX_HUMAN antibody, BAXA antibody, Baxdelta2G9 antibody, Baxdelta2G9omega antibody, Baxdelta2omega antibody, Bcl-2-like protein 4 antibody, BCL2 associated X protein antibody, BCL2 associated X protein omega antibody, BCL2 associated X protein transcript variant delta2 antibody, Bcl2-L-4 antibody, BCL2L4 antibody, membrane isoform alpha antibody

UniProt: Q07812

Pathways: Signalisation p53, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response