SCN4A anticorps

N° du produit ABIN7184120

Détail du produit anti-SCN4A anticorps

Antigène: SCN4A (Sodium Channel, Voltage-Gated, Type IV, alpha Subunit (SCN4A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCN4A est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from internal of Human SCN4A.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:3000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SCN4A

Antigène: SCN4A (Sodium Channel, Voltage-Gated, Type IV, alpha Subunit (SCN4A))

Autre désignation: SCN4A (SCN4A Produits)

Synonymes: anticorps Nav1.4, anticorps SkM1, anticorps mH2, anticorps HOKPP2, anticorps HYKPP, anticorps HYPP, anticorps NAC1A, anticorps Na(V)1.4, anticorps NCHVS, anticorps microI, anticorps Nav1.4b, anticorps sodium channel, voltage-gated, type IV, alpha, anticorps sodium voltage-gated channel alpha subunit 4, anticorps sodium channel, voltage-gated, type IV, alpha, b, anticorps Scn4a, anticorps SCN4A, anticorps scn4ab

Sujet:

Background: This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle.

George A.L. Jr., Ann. Neurol. 31:131-137(1992).
Wang J., Biochem. Biophys. Res. Commun. 182:794-801(1992).
Tsujino A., Proc. Natl. Acad. Sci. U.S.A. 100:7377-7382(2003).

Aliases: HYKPP antibody, HYPP antibody, Na(V)1.4 antibody, NAC1A antibody, Nav1.4 antibody, Scn4a antibody, SCN4A_HUMAN antibody, Skeletal muscle voltage dependent sodium channel type IV alpha subunit antibody, SkM1 antibody, Sodium channel protein skeletal muscle subunit alpha antibody, Sodium channel protein type 4 subunit alpha antibody, Sodium channel protein type IV subunit alpha antibody, Sodium channel voltage gated type IV alpha subunit antibody, Voltage gated sodium channel subunit alpha Nav1.4 antibody, Voltage gated sodium channel type 4 alpha antibody, Voltage-gated sodium channel subunit alpha Nav1.4 antibody

UniProt: P35499