SERPINA4 anticorps (AA 161-220)

N° du produit ABIN714731

Détail du produit anti-SERPINA4 anticorps

Antigène: SERPINA4 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 (SERPINA4))

Épitope: AA 161-220

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SERPINA4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris

Homologie: Human,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human KLST/Kallistatin (161-220aa)

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-SERPINA4 (ABIN714731)

Biswas, Maihofer, Mir, Rao, Zhang, Khandrika, Mahata, Friese, Hightower, Mahata, Baker, Nievergelt, Vaingankar, OConnor: "Polymorphisms at the F12 and KLKB1 loci have significant trait association with activation of the renin-angiotensin system." dans: BMC medical genetics, Vol. 17, pp. 21, (2016) (PubMed).

Détails sur SERPINA4

Antigène: SERPINA4 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 (SERPINA4))

Autre désignation: KLST (SERPINA4 Produits)

Synonymes: anticorps KLKR, anticorps Klk6, anticorps hK1, anticorps KAL, anticorps KLST, anticorps KST, anticorps PI-4, anticorps PI4, anticorps kallistatin, anticorps SERPINA4, anticorps DKFZp469E1737, anticorps KALps, anticorps Klst, anticorps kallikrein 1, anticorps serpin family A member 4, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4, anticorps serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1, anticorps KLK1, anticorps SERPINA4, anticorps Serpina4, anticorps SPIA4, anticorps Serpina4-ps1

Sujet:

Synonyms: Serpin peptidase inhibitor clade A member 4, Kallikrein binding protein, Kallikrein inhibitor, Protease inhibitor 4, Serpin A4, KAL, Kallikrein binding protein, Kallikrein inhibitor, KBP, KLST, KST, MGC108582, PI4, Protease inhibitor 4, Serpin A4, Serpin peptidase inhibitor clade A member 4, SERPINA4, KAIN_HUMAN.

Background: Kallistatin is a serine proteinase inhibitor which binds to tissue kallikrein and inhibits its amidolytic and kininogenase activity. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.

ID gène: 5267