ITGAV/ITGB6 anticorps

N° du produit ABIN714806

Détail du produit anti-ITGAV/ITGB6 anticorps

Antigène: ITGAV/ITGB6 (Integrin AlphaV Beta6 (ITGAV/ITGB6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGAV/ITGB6 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Integrin Alpha V + Beta 6

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-ITGAV/ITGB6 (ABIN714806)

Cargnoni, Farigu, Cotti Piccinelli, Bonassi Signoroni, Romele, Vanosi, Toschi, Cesari, Barros SantAnna, Magatti, Silini, Parolini: "Effect of human amniotic epithelial cells on pro-fibrogenic resident hepatic cells in a rat model of liver fibrosis." dans: Journal of cellular and molecular medicine, Vol. 22, Issue 2, pp. 1202-1213, (2017) (PubMed).

Gao, Gao, Zhang, Liu, Jia, Zhu, Wang, Liu: "A near-infrared phthalocyanine dye-labeled agent for integrin ?v?6-targeted theranostics of pancreatic cancer." dans: Biomaterials, Vol. 53, pp. 229-38, (2015) (PubMed).

Li, Huang, Gao, Chen, Zhang, Zheng: "Scutellarin inhibits the growth and invasion of human tongue squamous carcinoma through the inhibition of matrix metalloproteinase-2 and -9 and αvβ6 integrin." dans: International journal of oncology, Vol. 42, Issue 5, pp. 1674-81, (2013) (PubMed).

Détails sur ITGAV/ITGB6

Antigène: ITGAV/ITGB6 (Integrin AlphaV Beta6 (ITGAV/ITGB6))

Autre désignation: Integrin Alpha V + Beta 6 (ITGAV/ITGB6 Produits)

Sujet:

Synonyms: CD51, Integrin alpha-V light chain, integrin, alpha V vitronectin receptor, alpha polypeptide, antigen CD51, Integrin, alpha V, Integrin, beta 6, ITAV_HUMAN, ITGAV, ITGB6, Vitronectin receptor subunit alpha.

Background: Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin alpha-v beta-6 is upregulated in cancers and during tissue remodelling but is absent from resting adult tissues. Integrin alpha-v beta-6 promotes invasion and correlates with poor survival and therefore makes a promising therapeutic target.

ID gène: 36853694