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Podocin anticorps

NPHS2 Reactivité: Humain WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7342489
  • Antigène Voir toutes Podocin (NPHS2) Anticorps
    Podocin (NPHS2) (Nephrosis 2, Idiopathic, Steroid-Resistant (Podocin) (NPHS2))
    Reactivité
    • 5
    • 2
    • 1
    Humain
    Hôte
    • 5
    • 1
    Lapin
    Clonalité
    • 4
    • 2
    Polyclonal
    Conjugué
    • 6
    Cet anticorp Podocin est non-conjugé
    Application
    • 6
    • 3
    • 3
    • 3
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Antigen affinity purification
    Immunogène
    Synthetic peptide of Human NPHS2
    Isotype
    IgG
  • Indications d'application
    ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    Podocin (NPHS2) (Nephrosis 2, Idiopathic, Steroid-Resistant (Podocin) (NPHS2))
    Autre désignation
    NPHS2 (NPHS2 Produits)
    Synonymes
    anticorps PDCN, anticorps SRN1, anticorps AI790225, anticorps podocin, anticorps nephrosis 2, podocin, anticorps NPHS2, podocin, anticorps Nphs2, anticorps NPHS2
    Sujet

    Background: This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined.

    Aliases: nephrosis 2 antibody, Nephrosis 2, idiopathic, steroid resistant (podocin) antibody, nephrosis 2, idiopathic, steroid resistant antibody, NPHS2 antibody, NPHS2 gene antibody, PDCN antibody, PODO_HUMAN antibody, Podocin antibody, SRN1 antibody

    UniProt
    Q9NP85
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