NOXA anticorps (AA 1-54)

N° du produit ABIN7193484

Détail du produit anti-NOXA anticorps

Antigène: NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))

Épitope: AA 1-54

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NOXA est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: purified

Immunogène: Purified recombinant fragment of human PMAIP1 (AA: 1-54) expressed in E. coli.

Clone: 1A2D3

Isotype: IgG1

Information d'application

Indications d'application: WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur NOXA

Antigène: NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))

Autre désignation: PMAIP1 (PMAIP1 Produits)

Synonymes: anticorps TN3, anticorps PMAIP1, anticorps zgc:162379, anticorps APR, anticorps NOXA, anticorps Noxa, anticorps phorbol-12-myristate-13-acetate-induced protein 1, anticorps PMAIP1, anticorps pmaip1, anticorps Pmaip1

Sujet:

Description: The protein encoded by this gene promotes activation of caspases and apoptosis, Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.

Aliases: APR, NOXA

Poids moléculaire: 6 kDa

ID gène: 5366

Pathways: Signalisation p53, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus