GZMB anticorps (AA 21-247)

N° du produit ABIN7193680

Cet anticorps Souris Monoclonal détecte spécifiquement GZMB dans IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour GZMB anticorps (AA 21-247) (ABIN7193680)

Antigène: GZMB (Granzyme B (GZMB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GZMB est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Clone: 2G12G7

Détail du produit anti-GZMB anticorps

Épitope: AA 21-247

Fonction: GZMB Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human GZMB (AA: 21-247) expressed in E. Coli.

Isotype: IgG2a

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur GZMB

Antigène: GZMB (Granzyme B (GZMB))

Autre désignation: GZMB

Sujet:

This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]

Poids moléculaire: 28 kDa

UniProt: P10144

Pathways: Apoptose, Caspase Cascade in Apoptosis