GZMB anticorps

N° du produit ABIN108719

Détail du produit anti-GZMB anticorps

Antigène: GZMB (Granzyme B (GZMB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GZMB est non-conjugé

Application: ELISA, Flow Cytometry (FACS), Cell-ELISA (cELISA)

Specificité: GM4C1 recognises granzyme B transiently expressed on the cell surface of transfected BOSC cells as well as the native protein in peripheral blood mononuclear cells. The antibody does not cross-react with the human granzymes A, K or M (Fi

Purification: Protein G

Immunogène: genetic immunisation with cDNA encoding human Granzyme B

Clone: GM-4C1

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: 1.2 µg/10^6 cells
ELISA: 1:200 - 1:400
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Restrictions: For Research Use only

Stockage

Buffer: PBS, pH 7.2

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C

Stockage commentaire: short term: 2 °C - 8 °C, long term: -20 °C

Détails sur GZMB

Antigène: GZMB (Granzyme B (GZMB))

Autre désignation: Granzyme B (GZMB Produits)

Synonymes: anticorps CCPI, anticorps CGL-1, anticorps CGL1, anticorps CSP-B, anticorps CSPB, anticorps CTLA1, anticorps CTSGL1, anticorps HLP, anticorps SECT, anticorps granzyme B, anticorps GZMB

Sujet: Granzymes are exogenous serine proteases that are stored in the cytotoxic granules of activated T cells and NK cells. GM4C1 was generated by genetic immunisation and reacts with human granzyme B (GrB), a 27 kDa serine protease which cleaves target-cell proteins at specific aspartate residues.

UniProt: P10144

Pathways: Apoptose, Caspase Cascade in Apoptosis