FGF2 anticorps (AA 189-288)
Aperçu rapide pour FGF2 anticorps (AA 189-288) (ABIN7193683)
Antigène
Voir toutes FGF2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 189-288
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Fonction
- FGF2 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human FGF2 (AA: 189-288) expressed in E. Coli.
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Isotype
- IgG2a
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Indications d'application
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ELISA: 1/10000
FCM: 1/200-1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
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Autre désignation
- FGF2
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Sujet
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The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
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Poids moléculaire
- 30.8kd
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ID gène
- 2247
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UniProt
- P09038
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Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
Antigène
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