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CD11b anticorps (AA 623-728)

ITGAM Reactivité: Humain FACS, IHC, WB, ELISA Hôte: Souris Monoclonal 3A4B10 unconjugated

N° du produit ABIN7193892

Fiche de données

Antigène Voir toutes CD11b (ITGAM) Anticorps

CD11b (ITGAM) (Integrin alpha M (ITGAM))
Épitope
16

14

10

7

6

6

5

4

3

3

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 623-728
Reactivité
268

166

70

33

17

17

16

14

11

7

7

5

4

2

2

1
Humain
Hôte
150

105

99

2

1

1
Souris
Anticorps secondaires appropriés
Clonalité
262

92

1
Monoclonal
Conjugué
112

36

32

27

21

11

9

8

8

6

6

6

6

5

4

4

4

4

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp CD11b est non-conjugé
Application
267

81

77

76

59

40

37

22

20

20

13

13

12

6

5

5

5

4

3

2

2

2

2

1

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Purification

purified

Immunogène

Purified recombinant fragment of human ITGAM (AA: 623-728) expressed in E. coli.

Clone

3A4B10

Isotype

IgG1

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anti-Integrin alpha M (ITGAM) antibody (Biotin)
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ITGAM Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-174 FITC

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anti-Integrin alpha M (ITGAM) (AA 623-728) antibody
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anti-Integrin alpha M (ITGAM) (AA 941-1074) antibody
ITGAM Reactivité: Humain IHC, WB, StM Hôte: Souris Monoclonal ITGAM-3338 unconjugated

Indications d'application

WB:1:500 - 1:2000, IHC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,

Restrictions

For Research Use only
Buffer

Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C/-20 °C

Stockage commentaire

4°C, -20°C for long term storage
Antigène

CD11b (ITGAM) (Integrin alpha M (ITGAM))

Autre désignation

ITGAM (ITGAM Produits)

Synonymes

anticorps CD11b/CD18, anticorps CR3, anticorps CR3A, anticorps Cd11b, anticorps F730045J24Rik, anticorps Ly-40, anticorps MAC1, anticorps Mac-1, anticorps Mac-1a, anticorps CD11B, anticorps MAC-1, anticorps MAC1A, anticorps MO1A, anticorps SLEB6, anticorps C3bi, anticorps integrin subunit alpha M, anticorps integrin alpha M, anticorps integrin, alpha M (complement component 3 receptor 3 subunit), anticorps integrin alpha-M, anticorps ITGAM, anticorps Itgam, anticorps LOC100351865

Sujet

Description: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
Aliases: CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6

Poids moléculaire

127.1 kDa

ID gène

3684

Pathways

Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation