NCKAP1 anticorps (AA 1001-1132) (HRP)

N° du produit ABIN715745

L’anticorps Lapin Polyclonal anti-NCKAP1 a été validé pour WB et ELISA. Il convient pour détecter NCKAP1 dans des échantillons de Souris.

Aperçu rapide pour NCKAP1 anticorps (AA 1001-1132) (HRP) (ABIN715745)

Antigène: NCKAP1 (NCK Associated Protein 1 (NCKAP1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCKAP1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA

Détail du produit anti-NCKAP1 anticorps (HRP)

Épitope: AA 1001-1132

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Pig,Horse,Chicken,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NCKAP1L

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur NCKAP1

Antigène: NCKAP1 (NCK Associated Protein 1 (NCKAP1))

Autre désignation: NCKAP1

Sujet:

Synonyms: NCK associated protein 1, NCK associated protein 1, Membrane associated protein HEM2, Membrane-associated protein HEM-2, NAP 1, NAP1, NAP125, NCK associated protein, Nck-associated protein 1, Nckap1, NCKP1_HUMAN, p125Nap1.

Background: NAP125, also known as NCKAP1 (NCK-associated protein 1), p125Nap1 or membrane-associated protein HEM-2, is a 1,128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family. While widely expressed, NAP125 is found at highest levels in heart, brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, Abi-1 and CYFIP1. NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32.1 and mouse chromosome 2 C3. NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, suggesting a possible role in the disease.

ID gène: 10787

UniProt: P55160

Pathways: Signalisation RTK, Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis