CD247 anticorps
Aperçu rapide pour CD247 anticorps (ABIN7225870)
Antigène
Voir toutes CD247 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- CD3 ζ Polyclonal Antibody
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Specificité
- CD3 ζ Polyclonal Antibody detects endogenous levels of CD3 ζ protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from human CD3 zeta around the non-phosphorylation site of Y142
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CD247 (CD247 Molecule (CD247))
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Autre désignation
- CD3 zeta
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Sujet
- Rabbit Anti-CD3 ζ Polyclonal Antibody,CD247, CD3Z, T3Z, TCRZ, T-cell surface glycoprotein CD3 zeta chain, T-cell receptor T3 zeta chain, CD antigen CD247,The protein encoded by CD247 (CD247 Molecule) is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for CD247.,T-cell surface glycoprotein CD3 zeta chain
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Poids moléculaire
- observerd band 20kDa
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ID gène
- 919
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UniProt
- P20963
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Pathways
- TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
Antigène
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