FGF23 anticorps (AA 120-200)

N° du produit ABIN7225150

Cet anticorps anti-FGF23 Polyclonal Lapin (ABIN7225150) détecte spécifiquement FGF23 dans WB, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour FGF23 anticorps (AA 120-200) (ABIN7225150)

Antigène: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGF23 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-FGF23 anticorps

Épitope: AA 120-200

Fonction: Rabbit Anti-FGF-23 Polyclonal Antibody

Specificité: FGF-23 Polyclonal Antibody detects endogenous levels of FGF-23 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human FGF-23 at AA range: 120-200

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,IF 1:100-300,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur FGF23

Antigène: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Autre désignation: FGF-23

Sujet: FGF23, HYPF, Fibroblast growth factor 23, FGF-23, Phosphatonin, Tumor-derived hypophosphatemia-inducing factorFGF23 (fibroblast growth factor 23) encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in FGF23 are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC).

Poids moléculaire: 27kD

ID gène: 8074

UniProt: Q9GZV9

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion