FLT3 anticorps (pTyr599)

N° du produit ABIN7220670

Cet anticorps anti-FLT3 est un anticorps Lapin Polyclonal détectant FLT3 dans WB et ELISA. Adapté pour Humain, Souris et Singe.

Aperçu rapide pour FLT3 anticorps (pTyr599) (ABIN7220670)

Antigène: FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

Reactivité: Humain, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FLT3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-FLT3 anticorps

Épitope: pTyr599

Fonction: Flt3 (phospho Tyr599) Polyclonal Antibody

Specificité: Phospho-Flt3 (Y599) Polyclonal Antibody detects endogenous levels of Flt3 protein only when phosphorylated at Y599.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from human Flt3 Phospho-Tyr599

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur FLT3

Antigène: FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

Autre désignation: Flt3

Sujet: Rabbit Anti-Flt3 (phospho Tyr599) Polyclonal Antibody,FLT3, CD135, FLK2, STK1, Receptor-type tyrosine-protein kinase FLT3, FL cytokine receptor, Fetal liver kinase-2, FLK-2, Fms-like tyrosine kinase 3, FLT-3, Stem cell tyrosine kinase 1, STK-1, CD antigen CD135,FLT3 encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.,Receptor-type tyrosine-protein kinase FLT3

Poids moléculaire: observerd band 160kDa

ID gène: 2322

UniProt: P36888

Pathways: Signalisation RTK