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FLT3 anticorps

FLT3 Reactivité: Humain, Souris, Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7012052
  • Antigène Voir toutes FLT3 Anticorps
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    Reactivité
    • 160
    • 56
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 159
    • 17
    • 6
    • 1
    Lapin
    Clonalité
    • 160
    • 23
    Polyclonal
    Conjugué
    • 69
    • 15
    • 11
    • 9
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    Cet anticorp FLT3 est non-conjugé
    Application
    • 126
    • 69
    • 54
    • 54
    • 37
    • 26
    • 19
    • 14
    • 9
    • 9
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Recombinant protein of human FLT3
    Isotype
    IgG
    Top Product
    Discover our top product FLT3 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000 IHC 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    Autre désignation
    FLT3 (FLT3 Produits)
    Synonymes
    anticorps FLT3, anticorps B230315G04, anticorps CD135, anticorps Flk-2, anticorps Flk2, anticorps Flt-3, anticorps Ly72, anticorps wmfl, anticorps FLK-2, anticorps FLK2, anticorps STK1, anticorps fms related tyrosine kinase 3, anticorps FMS-like tyrosine kinase 3, anticorps fms-related tyrosine kinase 3, anticorps FLT3, anticorps Flt3
    Sujet
    This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
    Poids moléculaire

    Observed_MW: 113 kDa

    Calculated_MW: 108 kDa/112 kDa

    ID gène
    2322
    UniProt
    P36888
    Pathways
    Signalisation RTK
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