FOLR2 anticorps

N° du produit ABIN7228570

L’anticorps anti-FOLR2 Polyclonal Lapin est utilisé pour la détection de FOLR2 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour FOLR2 anticorps (ABIN7228570)

Antigène: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOLR2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-FOLR2 anticorps

Fonction: Rabbit Anti-FOLR2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of FOLR2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human FOLR2 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur FOLR2

Antigène: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Autre désignation: FOLR2

Sujet: Folate receptor beta, FR-beta, Folate receptor 2, Folate receptor, fetal/placental, Placental folate-binding protein, FBPFOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. FOLR2 (Folate Receptor Beta) is a Protein Coding gene. Diseases associated with FOLR2 include Neural Tube Defects and Rheumatoid Arthritis. Among its related pathways are Metabolism and Metabolism of water-soluble vitamins and cofactors.

Poids moléculaire: 28kD

ID gène: 2350

UniProt: P14207

Pathways: Dicarboxylic Acid Transport