HIRA anticorps

N° du produit ABIN7224842

Cet anticorps anti-HIRA est un anticorps Polyclonal produit chez le Lapin, détectant HIRA dans ELISA et IHC (p). Convient pour Humain et Souris.

Aperçu rapide pour HIRA anticorps (ABIN7224842)

Antigène: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIRA est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-HIRA anticorps

Fonction: HIRA Polyclonal Antibody

Specificité: HIRA Polyclonal Antibody detects endogenous levels of HIRA protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from human HIRA around the non-phosphorylation site of T555

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur HIRA

Antigène: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Autre désignation: HIRA

Sujet: Rabbit Anti-HIRA Polyclonal Antibody,HIRA, DGCR1, HIR, TUPLE1, Protein HIRA, TUP1-like enhancer of split protein 1,HIRA (histone cell cycle regulator) encodes a histone chaperone that preferentially places the variant histone H3. in nucleosomes. Orthologs of HIRA in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.,Protein HIRA

ID gène: 7290

UniProt: P54198

Pathways: Chromatin Binding