IFIT3 anticorps (AA 330-410)
Aperçu rapide pour IFIT3 anticorps (AA 330-410) (ABIN7229034)
Antigène
Voir toutes IFIT3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 330-410
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Fonction
- IFIT3 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of IFIT3 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human IFIT3 protein at AA range: 330-410
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- IFIT3 (Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3))
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Autre désignation
- IFIT3
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Sujet
- Rabbit Anti-IFIT3 Polyclonal Antibody,Interferon-induced protein with tetratricopeptide repeats 3, IFIT-3, CIG49, ISG-60, Interferon-induced 60 kDa protein, IFI-60K, Interferon-induced protein with tetratricopeptide repeats 4, IFIT-4, Retinoic acid-induced gene G protein, P60, RIG-G,IFIT3 (Interferon Induced Protein With Tetratricopeptide Repeats 3) is a Protein Coding gene. Among its related pathways are Interferon gamma signaling and Cytokine Signaling in Immune system. IFN-induced antiviral protein which acts as an inhibitor of cellular as well as viral processes, cell migration, proliferation, signaling, and viral replication. Enhances MAVS-mediated host antiviral responses by serving as an adapter bridging TBK1 to MAVS which leads to the activation of TBK1 and phosphorylation of IRF3 and phosphorylated IRF3 translocates into nucleus to promote antiviral gene transcription. Exihibits an antiproliferative activity via the up-regulation of cell cycle negative regulators CDKN1A/p21 and CDKN1B/p27.,IFIT3
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Poids moléculaire
- observerd band 53kDa
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ID gène
- 3437
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UniProt
- O14879
Antigène
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