IFIT3 anticorps (AA 330-410)

N° du produit ABIN7229034

Cet anticorps anti-IFIT3 Polyclonal Lapin (ABIN7229034) détecte spécifiquement IFIT3 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour IFIT3 anticorps (AA 330-410) (ABIN7229034)

Antigène: IFIT3 (Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFIT3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-IFIT3 anticorps

Épitope: AA 330-410

Fonction: Rabbit Anti-IFIT3 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of IFIT3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human IFIT3 protein at AA range: 330-410

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur IFIT3

Antigène: IFIT3 (Interferon-Induced Protein with Tetratricopeptide Repeats 3 (IFIT3))

Autre désignation: IFIT3

Sujet: Interferon-induced protein with tetratricopeptide repeats 3, IFIT-3, CIG49, ISG-60, Interferon-induced 60 kDa protein, IFI-60K, Interferon-induced protein with tetratricopeptide repeats 4, IFIT-4, Retinoic acid-induced gene G protein, P60, RIG-GIFIT3 (Interferon Induced Protein With Tetratricopeptide Repeats 3) is a Protein Coding gene. Among its related pathways are Interferon gamma signaling and Cytokine Signaling in Immune system. IFN-induced antiviral protein which acts as an inhibitor of cellular as well as viral processes, cell migration, proliferation, signaling, and viral replication. Enhances MAVS-mediated host antiviral responses by serving as an adapter bridging TBK1 to MAVS which leads to the activation of TBK1 and phosphorylation of IRF3 and phosphorylated IRF3 translocates into nucleus to promote antiviral gene transcription. Exihibits an antiproliferative activity via the up-regulation of cell cycle negative regulators CDKN1A/p21 and CDKN1B/p27.

Poids moléculaire: 53kD

ID gène: 3437

UniProt: O14879