JAK1 anticorps (pTyr1022)

N° du produit ABIN7205612

Cet anticorps Lapin Polyclonal détecte spécifiquement JAK1 dans WB, IHC, ELISA, IF et IP. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour JAK1 anticorps (pTyr1022) (ABIN7205612)

Antigène: JAK1 (Janus Kinase 1 (JAK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JAK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit anti-JAK1 anticorps

Épitope: pTyr1022

Fonction: Rabbit Anti-JAK1 (phospho Tyr1022) Polyclonal Antibody

Specificité: Phospho-JAK1 (Y1022) Polyclonal Antibody detects endogenous levels of JAK1 protein only when phosphorylated at Y1022.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human JAK1 Phospho-Tyr1022

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:50-200,WB 1:200-1:1000,IHC 1:100-1:300,ELISA 1:10000,Not yet tested in other applications,

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur JAK1

Antigène: JAK1 (Janus Kinase 1 (JAK1))

Autre désignation: JAK1

Sujet: JAK1, JAK1A, JAK1B, Tyrosine-protein kinase JAK1, Janus kinase 1, JAK-1JAK1 encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase (Janus kinase 1) phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 132kD

ID gène: 3716

UniProt: P23458

Pathways: Signalistation JAK/STAT, Signalisation RTK, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response