MAPK14 anticorps

N° du produit ABIN7230452

Cet anticorps Lapin Polyclonal détecte spécifiquement MAPK14 dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour MAPK14 anticorps (ABIN7230452)

Antigène: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK14 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MAPK14 anticorps

Fonction: p38 MAPK Polyclonal Antibody

Specificité: This antibody detects endogenous levels of p38 MAPK.

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human p38 MAPK protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur MAPK14

Antigène: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Autre désignation: p38 MAPK

Sujet: Rabbit Anti-p38 MAPK Polyclonal Antibody,Mitogen-activated protein kinase 14, MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAP kinase MXI2, MAX-interacting protein 2, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Stress-activated protein kinase 2a, SAPK2a,MAPK14 (Mitogen-Activated Protein Kinase 14) is a Protein Coding gene. Diseases associated with MAPK14 include Tuberculosis and Atherosclerosis. The protein encoded by MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.,p38 MAPK

Poids moléculaire: observerd band 42kDa

ID gène: 1432

UniProt: Q16539

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins